14-3-3 sigma/SFN Protein (AA 1-248, full length) (GST tag)
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- Target See all 14-3-3 sigma/SFN (SFN) Proteins
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-248
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This 14-3-3 sigma/SFN protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MERASLIQKA KLAEQAERYE DMAAFMKGAV EKGEELSCEE RNLLSVAYKN VVGGQRAAWR VLSSIEQKSN EEGSEEKGPE VREYREKVET ELQGVCDTVL GLLDSHLIKE AGDAESRVFY LKMKGDYYRY LAEVATGDDK KRIIDSARSA YQEAMDISKK EMPPTNPIRL GLALNFSVFH YEIANSPEEA ISLAKTTFDE AMADLHTLSE DSYKDSTLIM QLLRDNLTLW TADNAGEEGG EAPQEPQS
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product SFN Protein
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Stratifin (SFN) (AA 1-248) protein (GST tag)
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Stratifin (SFN) (AA 3-238) protein (GST tag)SFN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Stratifin (SFN) (AA 1-248) protein (Strep Tag)Crystallography grade SFN Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Stratifin (SFN) proteinSFN Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Stratifin (SFN) protein (Myc-DYKDDDDK Tag)SFN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
- Alternative Name
- 1433S (SFN Products)
- Synonyms
- YWHAS Protein, Er Protein, Mme1 Protein, Ywhas Protein, stratifin Protein, SFN Protein, Sfn Protein
- Background
- Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
- Molecular Weight
- 55.2 kDa
- UniProt
- P31947
- Pathways
- p53 Signaling, Myometrial Relaxation and Contraction
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