IL1F10 Protein (AA 1-152, full length) (His-SUMO Tag)

Catalog No. ABIN5711577

Product Details

Target: IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))

Protein Type: Recombinant

Protein Characteristics: full length, AA 1-152

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This IL1F10 protein is labelled with His-SUMO Tag.

Application: SDS-PAGE (SDS)

Sequence: MCSLPMARYY IIKYADQKAL YTRDGQLLVG DPVADNCCAE KICTLPNRGL DRTKVPIFLG IQGGSRCLAC VETEEGPSLQ LEDVNIEELY KGGEEATRFT FFQSSSGSAF RLEAAAWPGW FLCGPAEPQQ PVQLTKESEP SARTKFYFEQ SW

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))

Alternative Name: IL1FA (IL1F10 Products)

Synonyms: FIL1-theta Protein, IL-1HY2 Protein, IL-38 Protein, IL1-theta Protein, IL1HY2 Protein, interleukin 1 family, member 10 Protein, interleukin 1 family member 10 Protein, Il1f10 Protein, IL1F10 Protein

Background: Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.

Molecular Weight: 33 kDa

UniProt: Q8WWZ1