Ensa Protein (AA 1-121, full length) (GST tag)
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- Target See all Ensa (ENSA) Proteins
- Ensa (ENSA) (Endosulfine alpha (ENSA))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-121
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Ensa protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product ENSA Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- Ensa (ENSA) (Endosulfine alpha (ENSA))
- Alternative Name
- ENSA (ENSA Products)
- Synonyms
- ARPP-19e Protein, 1700020C18Rik Protein, 2610007F17Rik Protein, AI451924 Protein, ensa Protein, si:dkeyp-24a7.3 Protein, ensaa Protein, endosulfine alpha Protein, endosulfine alpha a Protein, endosulfine alpha S homeolog Protein, ENSA Protein, Ensa Protein, ensa Protein, ensaa Protein, ensa.S Protein
- Background
- Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase . Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.1 Publication
- Molecular Weight
- 40.8 kDa
- UniProt
- O43768
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