GRP78 Protein (AA 25-293, partial) (His tag)

Catalog No. ABIN5712375

Product Details

Target: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Protein Type: Recombinant

Protein Characteristics: partial, AA 25-293

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This GRP78 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: EDVGTVVGID LGTTYSCVGV FKNGRVEIIA NDQGNRITPS YVAFTPEGER LIGDAAKNQL TSNPENTVFD AKRLIGRTWN DPSVQQDIKF LPFKVVEKKT KPYIQVDIGG GQTKTFAPEE ISAMVLTKMK ETAEAYLGKK VTHAVVTVPA YFNDAQRQAT KDAGTIAGLN VMRIINEPTA AAIAYGLDKR EGEKNILVFD LGGGTFDVSL LTIDNGVFEV VATNGDTHLG GEDFDQRVME HFIKLYKKKT GKDVRKDNRA VQKLRREVE

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Alternative Name: GRP78 (HSPA5 Products)

Synonyms: GRP78 Protein, BiP Protein, GRP-78 Protein, grp78 Protein, hspa5a Protein, BIP Protein, MIF2 Protein, AL022860 Protein, AU019543 Protein, Bip Protein, D2Wsu141e Protein, D2Wsu17e Protein, Grp78 Protein, Hsce70 Protein, SEZ-7 Protein, Sez7 Protein, baffled Protein, mBiP Protein, cb865 Protein, fb60h09 Protein, fi36d04 Protein, wu:fb60h09 Protein, wu:fi36d04 Protein, zgc:55994 Protein, zgc:77606 Protein, 78 kDa glucose-regulated protein Protein, heat shock protein family A (Hsp70) member 5 Protein, BiP/GRP78 Protein, glucose-regulated protein 78 Protein, putative glucose-regulated protein 78 Protein, Hsp70 family ATPase KAR2 Protein, heat shock protein family A (Hsp70) member 5 S homeolog Protein, heat shock 70 kDa protein 5a Protein, heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) Protein, heat shock protein 5 Protein, heat shock protein family A member 5 Protein, CpipJ_CPIJ003550 Protein, HSPA5 Protein, grp78 Protein, LOC100533358 Protein, BiP/grp78 Protein, Tc00.1047053506585.40 Protein, Tb11.02.5450 Protein, Tb11.02.5500 Protein, LMJF_28_1200 Protein, KAR2 Protein, LOC100135840 Protein, hspa5.S Protein, hspa5 Protein, Hspa5 Protein

Background: Probably plays a role in facilitating the assbly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.

Molecular Weight: 33.7 kDa

UniProt: P11021

Pathways: Thyroid Hormone Synthesis, ER-Nucleus Signaling