Caveolin-1 Protein (AA 1-178) (His tag)

Catalog No. ABIN5713316

Product Details

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Protein Type: Recombinant

Protein Characteristics: AA 1-178

Origin: Dog

Source: Yeast

Purification tag / Conjugate: This Caveolin-1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MSGGKYVDSE GHLYTVPIRE QGNIYKPNNK AMAEEMSEKQ VYDAHTKEID LVNRDPKHLN DDVVKIDFED VIAEPEGTHS FDGIWKASFT TFTVTKYWFY RLLSALFGIP MALIWGIYFA ILSFLHIWAV VPCIKSFLIE IQCISRVYSI YVHTFCDPFF EAVGKIFSNI RINMQKET

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Alternative Name: CAV1 (CAV1 Products)

Synonyms: fc07c04 Protein, wu:fc07c04 Protein, Cav-1 Protein, bscl3 Protein, cav1 Protein, cav1a Protein, cgl3 Protein, vip21 Protein, cav1b Protein, caveolin-1 Protein, cav Protein, mstp085 Protein, Caveolin-1 Protein, CAV1 Protein, cav-1 Protein, Cav Protein, caveolin 1 Protein, BSCL3 Protein, CGL3 Protein, MSTP085 Protein, PPH3 Protein, VIP21 Protein, caveolin 1 Protein, caveolin 1 L homeolog Protein, caveolin 1 S homeolog Protein, caveolin 1, caveolae protein Protein, caveolin 1, caveolae protein, 22kDa Protein, Caveolin Protein, cav1 Protein, cav1.L Protein, cav1.S Protein, CAV1 Protein, Cav1 Protein, cav-1 Protein

Background: Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. May act as a scaffolding protein within caveolar mbranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Recruits CTNNB1 to caveolar mbranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

Molecular Weight: 22.6 kDa

UniProt: P33724

Pathways: Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals