COPS6 Protein (AA 1-327) (His tag)
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- Target See all COPS6 Proteins
- COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-327
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This COPS6 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MAAAAAAAAA TNGTGGSSGM EVDAAVVPSV MACGVTGSVS VALHPLVILN ISDHWIRMRS QEGRPVQVIG ALIGKQEGRN IEVMNSFELL SHTVEEKIII DKEYYYTKEE QFKQVFKELE FLGWYTTGGP PDPSDIHVHK QVCEIIESPL FLKLNPMTKH TDLPVSVFES VIDIINGEAT MLFAELTYTL ATEEAERIGV DHVARMTATG SGENSTVAEH LIAQHSAIKM LHSRVKLILE YVKASEAGEV PFNHEILREA YALCHCLPVL STDKFKTDFY DQCNDVGLMA YLGTITKTCN TMNQFVNKFN VLYDRQGIGR RMRGLFF
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product COPS6 Protein
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COP9 Signalosome Complex Subunit 6 (COPS6) (AA 218-327) protein (GST tag)
COPS6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
COP9 Signalosome Complex Subunit 6 (COPS6) (AA 1-327) protein (GST tag)COPS6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
COP9 Signalosome Complex Subunit 6 (COPS6) (AA 1-327) protein (Strep Tag)Crystallography grade COPS6 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
COP9 Signalosome Complex Subunit 6 (COPS6) (AA 1-324) protein (Strep Tag)Crystallography grade COPS6 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
COP9 Signalosome Complex Subunit 6 (COPS6) protein (Myc-DYKDDDDK Tag)COPS6 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M uREA, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))
- Alternative Name
- COPS6 (COPS6 Products)
- Synonyms
- CG6932 Protein, CH6 Protein, Csn6 Protein, Dch6 Protein, Dmel\\CG6932 Protein, zgc:112075 Protein, Sgn3 Protein, VIP/MOV34 Protein, CSN6 Protein, MOV34-34KD Protein, COP9 signalosome subunit 6 Protein, COP-9 SigNalosome subunit Protein, COPS6 Protein, Cops6 Protein, CSN6 Protein, cops6 Protein, csn-6 Protein
- Background
- COPS6 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. Recombinant human COPS6 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 38.9kDa (347aa)
- NCBI Accession
- NP_006824
- UniProt
- Q7L5N1
- Pathways
- Cell Division Cycle
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