ATP1B1 Protein (AA 63-303) (His tag)

Catalog No. ABIN5853178

Product Details

Target: ATP1B1 (ATPase, Na+/K+ Transporting, beta 1 Polypeptide (ATP1B1))

Protein Type: Recombinant

Protein Characteristics: AA 63-303

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This ATP1B1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSEFKPTYQ DRVAPPGLTQ IPQIQKTEIS FRPNDPKSYE AYVLNIVRFL EKYKDSAQRD DMIFEDCGDV PSEPKERGDF NHERGERKVC RFKLEWLGNC SGLNDETYGY KEGKPCIIIK LNRVLGFKPK PPKNESLETY PVMKYNPNVL PVQCTGKRDE DKDKVGNVEY FGLGNSPGFP LQYYPYYGKL LQPKYLQPLL AVQFTNLTMD TEIRIECKAY GENIGYSEKD RFQGRFDVKI EVKS

Purity: > 90 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Denatured

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol, 0.4M urea

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: ATP1B1 (ATPase, Na+/K+ Transporting, beta 1 Polypeptide (ATP1B1))

Alternative Name: ATP1B1 (ATP1B1 Products)

Synonyms: ATP1B Protein, Atp4b Protein, Atpb Protein, Atpb-1 Protein, NKbeta1 Protein, ATPBS Protein, atp1b1 Protein, atp1b1a Protein, cb710 Protein, ATPase Na+/K+ transporting subunit beta 1 Protein, ATPase, Na+/K+ transporting, beta 1 polypeptide Protein, ATPase beta chain Protein, ATP synthase CF1 beta subunit Protein, ATPase Na+/K+ transporting subunit beta 1 S homeolog Protein, ATPase, Na+/K+ transporting, beta 1b polypeptide Protein, ATP1B1 Protein, Atp1b1 Protein, atpB Protein, atp1b1.S Protein, atp1b1b Protein

Background: ATP1B1 belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. ATP1B1 is a beta 1 subunit. Recombinant human ATP1B1 protein, fused to His-tag at N-terminus, was expressed in E.coli .

Molecular Weight: 30.4kDa (264aa)

NCBI Accession: NP_001668

UniProt: P05026

Pathways: Thyroid Hormone Synthesis, Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome