WNT7A Protein (AA 32-349) (His tag)

Catalog No. ABIN5853283

Product Details

Target: WNT7A (Wingless-Type MMTV Integration Site Family, Member 7A (WNT7A))

Protein Type: Recombinant

Protein Characteristics: AA 32-349

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This WNT7A protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSLGASIIC NKIPGLAPRQ RAICQSRPDA IIVIGEGSQM GLDECQFQFR NGRWNCSALG ERTVFGKELK VGSREAAFTY AIIAAGVAHA ITAACTQGNL SDCGCDKEKQ GQYHRDEGWK WGGCSADIRY GIGFAKVFVD AREIKQNART LMNLHNNEAG RKILEENMKL ECKCHGVSGS CTTKTCWTTL PQFRELGYVL KDKYNEAVHV EPVRASRNKR PTFLKIKKPL SYRKPMDTDL VYIEKSPNYC EEDPVTGSVG TQGRACNKTA PQASGCDLMC CGRGYNTHQY ARVWQCNCKF HWCCYVKCNT CSERTEMYTC K

Purity: > 85 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Denatured

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol, 0.4M urea

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: WNT7A (Wingless-Type MMTV Integration Site Family, Member 7A (WNT7A))

Alternative Name: WNT7A (WNT7A Products)

Synonyms: wnt7a Protein, AI849442 Protein, Wnt-7a Protein, px Protein, tw Protein, Xwnt-7a Protein, wnt-7a Protein, wnt7a-A Protein, Wnt family member 7A Protein, wingless-type MMTV integration site family, member 7Aa Protein, wingless-type MMTV integration site family, member 7A Protein, wingless-type MMTV integration site family member 7A S homeolog Protein, WNT7A Protein, wnt7aa Protein, Wnt7a Protein, wnt7a.S Protein

Background: WNT7A is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes. Recombinant human WNT7A protein, fused to His-tag at N-terminus, was expressed in E.coli .

Molecular Weight: 38.0 kDa (341aa)

NCBI Accession: NP_004616

UniProt: O00755

Pathways: WNT Signaling, Stem Cell Maintenance, Asymmetric Protein Localization