M6PR Protein (AA 27-185) (His tag)
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- Target See all M6PR Proteins
- M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-185
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This M6PR protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSTEEKTCD LVGEKGKESE KELALVKRLK PLFNKSFEST VGQGSDTYIY IFRVCREAGN HTSGAGLVQI NKSNGKETVV GRLNETHIFN GSNWIMLIYK GGDEYDNHCG KEQRRAVVMI SCNRHTLADN FNPVSEERGK VQDCFYLFEM DSSLACSPEI SH
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product M6PR Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))
- Alternative Name
- M6PR (M6PR Products)
- Synonyms
- CD222 Protein, CIMPR Protein, M6P-R Protein, MPR1 Protein, MPRI Protein, CD-MPR Protein, MPR 46 Protein, MPR-46 Protein, MPR46 Protein, SMPR Protein, Mpr46 Protein, CDMPR Protein, m6pr Protein, MGC68896 Protein, MGC130765 Protein, zgc:77757 Protein, wu:fj81h11 Protein, MGC89423 Protein, M6PR Protein, mprd Protein, C16orf27 Protein, GNPTAG Protein, LP2537 Protein, RJD9 Protein, insulin like growth factor 2 receptor Protein, mannose-6-phosphate receptor, cation dependent Protein, mannose-6-phosphate receptor (cation dependent) L homeolog Protein, mannose-6-phosphate receptor (cation dependent) Protein, mannose-6-phosphate receptor (cation dependent) S homeolog Protein, Cation-dependent mannose-6-phosphate receptor Protein, N-acetylglucosamine-1-phosphate transferase gamma subunit Protein, IGF2R Protein, M6PR Protein, M6pr Protein, m6pr.L Protein, m6pr Protein, m6pr.S Protein, Ethha_1678 Protein, mprd Protein, GNPTG Protein
- Background
- M6PR is a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. This protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. Recombinant human M6PR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques..
- Molecular Weight
- 20.3kDa (182aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_002346
- UniProt
- P20645
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