Neurogranin Protein (NRGN) (AA 1-78) (His tag)
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- Target See all Neurogranin (NRGN) Proteins
- Neurogranin (NRGN)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-78
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Neurogranin protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMDCCTEN ACSKPDDDIL DIPLDDPGAN AAAAKIQASF RGHMARKKIK SGERGRKGPG PGGPGGAGVA RGGAGGGPSG D
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product NRGN Protein
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Neurogranin (NRGN) (AA 1-78) protein (GST tag)
NRGN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Neurogranin (NRGN) (AA 1-78) protein (His tag)NRGN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Neurogranin (NRGN) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)NRGN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Neurogranin (NRGN) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)NRGN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. 20 mM Tris-HCl buffer ( pH 7.0) containing 30 % glycerol 0.1 mM PMSF,1 mM EDTA
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Neurogranin (NRGN)
- Alternative Name
- NRGN (NRGN Products)
- Synonyms
- RC3 Protein, hng Protein, 0710001B06Rik Protein, AI838505 Protein, NG Protein, NG/RC3 Protein, Pss1 Protein, R75334 Protein, zgc:158686 Protein, neurogranin Protein, neurogranin (protein kinase C substrate, RC3) b Protein, NRGN Protein, Nrgn Protein, nrgnb Protein
- Background
- NRGN, also known as Neurogranin, is a calmodulin-binding protein expressed exclusively in the brain, particularly in dendritic spines, and participating in the protein kinase C signaling pathway. This protein is the main postsynaptic protein regulating the availability of calmodulin, binding to it in the absence of calcium. Phosphorylation by protein kinase C lowers its binding ability. Recombinant human NRGN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography
- Molecular Weight
- 10.0 kDa(101aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
- NCBI Accession
- NP_001119653
- UniProt
- Q92686
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