PLA2G7 Protein (AA 47-441) (His tag)
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- Target See all PLA2G7 (Lp-PLA2) Proteins
- PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 47-441
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PLA2G7 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSAAASFGQ TKIPRGNGPY SVGCTDLMFD HTNKGTFLRL YYPSQDNDRL DTLWIPNKEY FWGLSKFLGT HWLMGNILRL LFGSMTTPAN WNSPLRPGEK YPLVVFSHGL GAFRTLYSAI GIDLASHGFI VAAVEHRDRS ASATYYFKDQ SAAEIGDKSW LYLRTLKQEE ETHIRNEQVR QRAKECSQAL SLILDIDHGK PVKNALDLKF DMEQLKDSID REKIAVIGHS FGGATVIQTL SEDQRFRCGI ALDAWMFPLG DEVYSRIPQP LFFINSEYFQ YPANIIKMKK CYSPDKERKM ITIRGSVHQN FADFTFATGK IIGHMLKLKG DIDSNVAIDL SNKASLAFLQ KHLGLHKDFD QWDCLIEGDD ENLIPGTNIN TTNQHIMLQN SSGIEKYN
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product Lp-PLA2 Protein
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Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 22-440) protein (His tag)
Lp-PLA2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 22-441) protein (His tag)Lp-PLA2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 22-441) protein (GST tag)Lp-PLA2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 22-441) protein (His tag)Crystallography grade Lp-PLA2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol,
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))
- Alternative Name
- PLA2G7 (Lp-PLA2 Products)
- Synonyms
- LDL-PLA2 Protein, LP-PLA2 Protein, PAFAD Protein, PAFAH Protein, Lp-PLA2 Protein, PAF-AH Protein, R75400 Protein, zgc:77563 Protein, phospholipase A2 group VII Protein, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) Protein, PLA2G7 Protein, Pla2g7 Protein, pla2g7 Protein
- Background
- PLA2G7(platelet-activating factor acetylhydrolase), also known as lipoprotein-associated phospholipase A2, is a phospholipase A2 enzyme. It is a secreted enzyme which catalyzes the degradation of platelet-activating factor to biologically inactive products. This protein is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. In the blood, PLA2G7 goes mainly with LDL and less than 20 % is coupled with HDL. It is implicated in the development of atherosclerosis and is also a marker for cardiac disease. It might have a major physiologic effect in the presence of inflammatory bodily responses. Recombinant human PLA2G7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
- Molecular Weight
- 47.2 kDa(418aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_001161829
- UniProt
- Q13093
- Pathways
- Peptide Hormone Metabolism
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