Epiregulin Protein (EREG) (AA 63-108) (His tag)
-
- Target See all Epiregulin (EREG) Proteins
- Epiregulin (EREG)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 63-108
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Epiregulin protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSVSITKCS SDMNGYCLHG QCIYLVDMSQ NYCRCEVGYT GVRCEHFFL
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product EREG Protein
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
-
Denatured
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
-
- Target
- Epiregulin (EREG)
- Alternative Name
- EREG (EREG Products)
- Synonyms
- EREG Protein, ER Protein, EPR Protein, proepiregulin Protein, epiregulin Protein, EREG Protein, ereg Protein, Ereg Protein
- Background
- EREG, also known as epiregulin, is a member of the epidermal growth factor family. It can function as a ligand of EGFR (epidermal growth factor receptor), as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. It may be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis. Recombinant human EREG protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 7.7 kDa(69aa)
- NCBI Accession
- NP_001423
- UniProt
- O14944
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
-