PRKAA1 Protein (AA 1-279) (His tag)
-
- Target See all PRKAA1 Proteins
- PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-279
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PRKAA1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMRRLSSW RKMATAEKQK HDGRVKIGHY ILGDTLGVGT FGKVKVGKHE LTGHKVAVKI LNRQKIRSLD VVGKIRREIQ NLKLFRHPHI IKLYQVISTP SDIFMVMEYV SGGELFDYIC KNGRLDEKES RRLFQQILSG VDYCHRHMVV HRDLKPENVL LDAHMNAKIA DFGLSNMMSD GEFLRTSCGS PNYAAPEVIS GRLYAGPEVD IWSSGVILYA LLCGTLPFDD DHVPTLFKKI CDGIFYTPQY LNPSVISLLK HMLQVDPMKR ATIKDIREHE WF
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product PRKAA1 Protein
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid, In 20 mM Tris-HCl buffer( pH 8.0) containing 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
-
- Target
- PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
- Alternative Name
- PRKAA,1 (PRKAA1 Products)
- Synonyms
- AMPK Protein, AMPKa1 Protein, cb116 Protein, im:7154392 Protein, sb:cb130 Protein, wu:fa94c10 Protein, AMPK1 Protein, AMPKalpha1 Protein, AI194361 Protein, AI450832 Protein, AL024255 Protein, C130083N04Rik Protein, ampk Protein, ampka1 Protein, PRKAA1 Protein, protein kinase AMP-activated catalytic subunit alpha 1 Protein, protein kinase, AMP-activated, alpha 1 catalytic subunit Protein, protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog Protein, PRKAA1 Protein, prkaa1 Protein, Prkaa1 Protein, prkaa1.L Protein
- Background
- PRKAA1 also known as 5-AMP-activated protein kinase catalytic subunit alpha-1 isoform 1. PRKAA1 is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinasen activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Recombinant human PRKAA1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 34.3kDa (302aa)
- NCBI Accession
- NP_006242
- UniProt
- Q13131
- Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
-