PRSS3 Protein (AA 81-304) (His tag)

Catalog No. ABIN7281057

Product Details

Target: PRSS3 (Protease, serine, 3 (PRSS3))

Protein Type: Recombinant

Protein Characteristics: AA 81-304

Origin: Human

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This PRSS3 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: ADPIVGGYTC EENSLPYQVS LNSGSHFCGG SLISEQWVVS AAHCYKTRIQ VRLGEHNIKV LEGNEQFINA AKIIRHPKYN RDTLDNDIML IKLSSPAVIN ARVSTISLPT APPAAGTECL ISGWGNTLSF GADYPDELKC LDAPVLTQAE CKASYPGKIT NSMFCVGFLE GGKDSCQRDS GGPVVCNGQL QGVVSWGHGC AWKNRPGVYT KVYNYVDWIK DTIAANSHHH HHH

Purity: > 95 % by SDS - PAGE

Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: PRSS3 (Protease, serine, 3 (PRSS3))

Alternative Name: Trypsin-3 (PRSS3 Products)

Synonyms: MTG Protein, PRSS4 Protein, T9 Protein, TRY3 Protein, TRY4 Protein, Try3 Protein, Tb Protein, prss3 Protein, protease, serine 3 Protein, trypsin-3 Protein, protease, serine, 3 Protein, trypsin III Protein, protease, serine 3 L homeolog Protein, PRSS3 Protein, CpipJ_CPIJ016105 Protein, Prss3 Protein, trp-iii Protein, prss3.L Protein

Background: PRSS3, also known as trypsin-3, is a member of the trypsin family of serine proteases. It is specialized for the degradation of trypsin inhibitors and may be involved in defensin processing, including DEFA5. This protein is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Compared to PRSS1 and 2, one intriguing feature of PRSS3 is its resistance to polypeptide trypsin inhibitors, such as the Kunitz-type soybean trypsin inhibitor or the Kazal-type pancreatic secretory trypsin inhibitor. Recombinant human PRSS3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 25.3kDa (233aa) 28-40KDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_031369

UniProt: P35030