RTN4R Protein (AA 27-447) (His tag)
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- Target See all RTN4R Proteins
- RTN4R (Reticulon 4 Receptor (RTN4R))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-447
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This RTN4R protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- CPGACVCYNE PKVTTSCPQQ GLQAVPVGIP AASQRIFLHG NRISHVPAAS FRACRNLTIL WLHSNVLARI DAAAFTGLAL LEQLDLSDNA QLRSVDPATF HGLGRLHTLH LDRCGLQELG PGLFRGLAAL QYLYLQDNAL QALPDDTFRD LGNLTHLFLH GNRISSVPER AFRGLHSLDR LLLHQNRVAH VHPHAFRDLG RLMTLYLFAN NLSALPTEAL APLRALQYLR LNDNPWVCDC RARPLWAWLQ KFRGSSSEVP CSLPQRLAGR DLKRLAANDL QGCAVATGPY HPIWTGRATD EEPLGLPKCC QPDAADKASV LEPGRPASAG NALKGRVPPG DSPPGNGSGP RHINDSPFGT LPGSAEPPLT AVRPEGSEPP GFPTSGPRRR PGCSRKNRTR SHCRLGQAGS GGGGTGDSEG SLEHHHHHH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product RTN4R Protein
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Reticulon 4 Receptor (RTN4R) (AA 1-473) protein (GST tag)
RTN4R Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Reticulon 4 Receptor (RTN4R) (Active) protein (His tag)RTN4R Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Reticulon 4 Receptor (RTN4R) (Active) protein (His tag,Fc Tag)RTN4R Origin: Mouse Host: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
Reticulon 4 Receptor (RTN4R) (AA 27-447) protein (His tag)Crystallography grade RTN4R Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Reticulon 4 Receptor (RTN4R) (AA 27-447) protein (His tag)Crystallography grade RTN4R Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- RTN4R (Reticulon 4 Receptor (RTN4R))
- Alternative Name
- RTN4R (RTN4R Products)
- Synonyms
- NgR Protein, NGR Protein, NOGOR Protein, NgR1 Protein, Nogor Protein, reticulon 4 receptor Protein, rtn4r Protein, RTN4R Protein, Rtn4r Protein
- Background
- RTN4R, also known as reticulon-4 receptor, is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family including three members. It is expressed predominantly in neurons and their axons in the central nervous systems (CNS). It may be proposed as a potential drug target for treatment of various neurological conditions such as spinal cord injury, CNS lesions, peripheral nerve injury, stroke and Alzheimer's disease (AD). It may play a role in regulating the function of the gap junctions. Recombinant human RTN4R, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 46.3kDa (429aa) 40-57kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_075380
- UniProt
- Q9BZR6
- Pathways
- Neurotrophin Signaling Pathway
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