Retinoic Acid Early Transcript 1E (RAET1E) (AA 31-225) protein (hIgG-His-tag)
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- Target See all Retinoic Acid Early Transcript 1E (RAET1E) Proteins
- Retinoic Acid Early Transcript 1E (RAET1E)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 31-225
- Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- hIgG-His-tag
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPHSLCFNF TIKSLSRPGQ PWCEAQVFLN KNLFLQYNSD NNMVKPLGLL GKKVYATSTW GELTQTLGEV GRDLRMLLCD IKPQIKTSDP STLQVEMFCQ REAERCTGAS WQFATNGEKS LLFDAMNMTW TVINHEASKI KETWKKDRGL EKYFRKLSKG DCDHWLREFL GHWEAMPEPT VSPVNASDIH WSSSSLPDVE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG KHHHHHH
- Purity
- > 85 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product RAET1E Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Retinoic Acid Early Transcript 1E (RAET1E)
- Alternative Name
- RAET1E (RAET1E Products)
- Synonyms
- LETAL Protein, N2DL-4 Protein, NKG2DL4 Protein, RAET1E2 Protein, RL-4 Protein, ULBP4 Protein, bA350J20.7 Protein, retinoic acid early transcript 1E Protein, RAET1E Protein, Raet1e Protein
- Background
- RAET1E, also known as NKG2D ligand 4 isoform 1, is a member of the RAET1/ULBP family of cell surface protein that function as ligands for NKG2D. This protein is abnormally expressed on most colon cancer and some other tumor cell lines and virus infected peripheral blood cells. It binds and co-stimulates NKG2D expressing effector cells including NK cells, NKT cells, gamma delta T cells, and CD8+ alpha beta T cells, activating cytolytic activity and/or cytokine production. Also, it functions as a stress-induced ligand for NKG2D receptor. Recombinant human RAET1E, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 49.6kDa (437aa) 57-70kDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_631904
- UniProt
- Q8TD07
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