BST1 Protein (AA 33-293) (His tag)

Catalog No. ABIN5855163

Product Details

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Protein Type: Recombinant

Protein Characteristics: AA 33-293

Origin: Human

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This BST1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: RWRGEGTSAH LRDIFLGRCA EYRALLSPEQ RNKNCTAIWE AFKVALDKDP CSVLPSDYDL FINLSRHSIP RDKSLFWENS HLLVNSFADN TRRFMPLSDV LYGRVADFLS WCRQKNDSGL DYQSCPTSED CENNPVDSFW KRASIQYSKD SSGVIHVMLN GSEPTGAYPI KGFFADYEIP NLQKEKITRI EIWVMHEIGG PNVESCGEGS MKVLEKRLKD MGFQYSCIND YRPVKLLQCV DHSTHPDCAL KSAAAATQRK AHHHHHH

Purity: > 95 % by SDS - PAGE

Endotoxin Level: < 0.1 EU per 1ug of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Alternative Name: BST1 (BST1 Products)

Synonyms: BST1 Protein, 114/A10 Protein, A530073F09 Protein, BP-3 Protein, Bp3 Protein, Bsta1 Protein, CD157 Protein, Ly65 Protein, bone marrow stromal cell antigen 1 Protein, BST1 Protein, Bst1 Protein

Background: BST1, also known as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2, is a glycosylphosphatidyl inositol (GPI) anchored membrane protein that belongs to the CD38 family. It was originally identified as a bone marrow stromal cell molecule. This protein is an ectoenzyme sharing several characteristics with ADP-ribosyl cyclase CD38. Along with CD38, it exhibits both DP-ribosyl cyclase and cyclinc ADP ribose hydrolase activities. It may play a role in rheumatoid arthritis (RA) due to its enhanced expression in RA-derived bone marrow stromal cell lines. Also, it is expressed by cells of the myeloid lineage and could act as a receptor with signal transduction capability. Recombinant human BST1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 30.5kDa (267aa) 28-40kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_004325

UniProt: Q10588