IFNA7 Protein (AA 24-189) (His tag)
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- Target See all IFNA7 (IFNa7) Proteins
- IFNA7 (IFNa7) (Interferon, alpha 7 (IFNa7))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-189
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This IFNA7 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPCDLPQTH SLRNRRALIL LAQMGRISPF SCLKDRHEFR FPEEEFDGHQ FQKTQAISVL HEMIQQTFNL FSTEDSSAAW EQSLLEKFST ELYQQLNDLE ACVIQEVGVE ETPLMNEDFI LAVRKYFQRI TLYLMEKKYS PCAWEVVRAE IMRSFSFSTN LKKGLRRKDH HHHHH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product IFNa7 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- IFNA7 (IFNa7) (Interferon, alpha 7 (IFNa7))
- Alternative Name
- IFNA7 (IFNa7 Products)
- Synonyms
- CaIFN-alpha 7 Protein, Ifa7 Protein, IFN-alphaJ Protein, IFNA-J Protein, interferon, alpha 7 Protein, interferon alpha-7 Protein, interferon alpha 7 Protein, IFNA7 Protein, LOC741747 Protein, Ifna7 Protein
- Background
- IFNA7, also known as interferon alpha-7, is a member of the interferon family. Interferon promotes the production of two enzymes, protein kinase and oligoadenylate synthetase. They allow the cells to communicate with the protective barrier of the immune system to eradicate pathogens or tumors. IFNs are divided on the sequence of amino-acids into three groups: Alpha, Beta and Gamma interferons. IFN-alpha has both anti-viral and immunomodulatory activities on target cells, and increases the awareness of infection or tumor cells by elevating antigen presentation to T lymphocytes. This protein has both anti-viral and immunomodulatory activities on target cells and involved both in ligand binding and signal transduction. Recombinant human IFNA7, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 20.7kDa (175aa) 18-28kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_066401
- UniProt
- P01567
- Pathways
- JAK-STAT Signaling, Hepatitis C
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