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FLT4 Protein (AA 25-770) (Fc Tag)

FLT4 Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN5954972
  • Target See all FLT4 Proteins
    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 25-770
    Origin
    • 21
    • 4
    • 3
    • 2
    Mouse
    Source
    • 14
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This FLT4 protein is labelled with Fc Tag.
    Sequence
    AA 25-770
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 0.1 EU per μg by the LAL method.
    Top Product
    Discover our top product FLT4 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 100 mM Glycine, pH 7.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
  • Target
    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
    Alternative Name
    VEGF R3 (FLT4 Products)
    Synonyms
    FLT41 Protein, LMPH1A Protein, PCL Protein, VEGFR3 Protein, AI323512 Protein, Chy Protein, Flt-4 Protein, VEGFR-3 Protein, Vegfr3 Protein, cb1059 Protein, fms related tyrosine kinase 4 Protein, FMS-like tyrosine kinase 4 Protein, fms-related tyrosine kinase 4 Protein, FLT4 Protein, Flt4 Protein, flt4 Protein
    Background
    Vascular endothelial growth factor receptor 3 (VEGF R3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). VEGF R3 mediates lymphangiogenesis in response to VEGF-C and VEGF-D. VEGF R3 is widely expressed in the early embryo but becomes restricted to lymphatic endothelia at later stages of development. It is likely that VEGF R3 may be important for lymph angiogenesis.
    Molecular Weight
    111.5 kDa
    NCBI Accession
    NP_032055
    Pathways
    RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
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