RAD23A Protein (AA 2-201, partial) (GST tag)
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- Target See all RAD23A Proteins
- RAD23A (RAD23 Homolog A (RAD23A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-201, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RAD23A protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS), ELISA, Western Blotting (WB)
- Sequence
- AVTITLKTLQ QQTFKIRMEP DETVKVLKEK IEAEKGRDAF PVAGQKLIYA GKILSDDVPI RDYRIDEKNF VVVMVTKTKA GQGTSAPPEA SPTAAPESST SFPPAPTSGM SHPPPAARED KSPSEESAPT TSPESVSGSV PSSGSSGREE DAASTLVTGS EYETMLTEIM SMGYERERVV AALRASYNNP HRAVEYLLTG
- Purity
- 95 %
- Top Product
- Discover our top product RAD23A Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS buffer, 20mM GSH
- Storage
- 4 °C
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- Target
- RAD23A (RAD23 Homolog A (RAD23A))
- Alternative Name
- UV excision repair protein RAD23 homolog A (RAD23A Products)
- Synonyms
- rad23a Protein, wu:fe11h06 Protein, zgc:92001 Protein, RAD23A Protein, HHR23A Protein, HR23A Protein, 2310040P19Rik Protein, AL024030 Protein, mHR23A Protein, RAD23 homolog A, nucleotide excision repair protein a Protein, RAD23 homolog A, nucleotide excision repair protein Protein, rad23aa Protein, RAD23A Protein, Rad23a Protein
- Background
- Background: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. Ref.6 Ref.9 Ref.10 Ref.11 Ref.20 Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair (GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC. Ref.6 Ref.9 Ref.10 Ref.11 Ref.20 Involved in vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 vpr with the host proteasome. Synonyms: Short name=HR23A Short name=hHR23A
- Molecular Weight
- 48.8 kD
- NCBI Accession
- NM_005053
- UniProt
- P54725
- Pathways
- DNA Damage Repair
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