AATF Protein (AA 6-294, partial) (GST tag)
-
- Target See all AATF Proteins
- AATF (Apoptosis Antagonizing Transcription Factor (AATF))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 6-294, partial
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This AATF protein is labelled with GST tag.
- Application
- Western Blotting (WB), SDS-PAGE (SDS), ELISA
- Sequence
- PLALQLEQLL NPRPSEADPE ADPEEATAAR VIDRFDEGED GEGDFLVVGS IRKLASASLL DTDKRYCGKT TSRKAWNEDH WEQTLPGSSD EEISDEEGSG DEDSEGLGLE EYDEDDLGAA EEQECGDHRE SKKSRSHSAK TPGFSVQSIS DFEKFTKGMD DLGSSEEEED EESGMEEGDD AEDSQGESEE DRAGDRNSED DGVVMTFSSV KVSEEVEKGR AVKNQIALWD QLLEGRIKLQ KALLTTNQLP QPDVFPLFKD KGGPEFSSAL KNSHKALKAL LRSLVGLQE
- Purity
- 95 %
- Top Product
- Discover our top product AATF Protein
-
Apoptosis Antagonizing Transcription Factor (AATF) (AA 151-250) protein (GST tag)
AATF Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Apoptosis Antagonizing Transcription Factor (AATF) (AA 1-560) protein (GST tag)AATF Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Apoptosis Antagonizing Transcription Factor (AATF) (AA 2-560) protein (His tag)Crystallography grade AATF Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Apoptosis Antagonizing Transcription Factor (AATF) (AA 2-526) protein (His tag)Crystallography grade AATF Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Apoptosis Antagonizing Transcription Factor (AATF) protein (DYKDDDDK Tag)AATF Origin: Human Host: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Apoptosis Antagonizing Transcription Factor (AATF) proteinAATF Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- PBS buffer, 20mM GSH
- Storage
- 4 °C
-
- Target
- AATF (Apoptosis Antagonizing Transcription Factor (AATF))
- Alternative Name
- Protein AATF (AATF Products)
- Synonyms
- AATF Protein, ded Protein, che1 Protein, che-1 Protein, cb109 Protein, sb:cb109 Protein, wu:fc13d05 Protein, zgc:162071 Protein, CHE-1 Protein, CHE1 Protein, DED Protein, 4933415H02Rik Protein, 5830465M17Rik Protein, Che-1 Protein, Trb Protein, Ded Protein, apoptosis antagonizing transcription factor Protein, Apoptosis antagonizing transcription factor Protein, apoptosis antagonizing transcription factor S homeolog Protein, AATF Protein, aatf Protein, BFR2 Protein, NAEGRDRAFT_56916 Protein, Aatf Protein, aatf.S Protein
- Background
- Background: May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer disease (presenile and senile dementia), although the molecular basis for this phenomenon has not been described to date. Synonyms: Apoptosis-antagonizing transcription factor Rb-binding protein Che-1.
- Molecular Weight
- 59.1 kD
- NCBI Accession
- NM_012138
- UniProt
- Q9NY61
- Pathways
- Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
-
