Prolactin Receptor Protein (PRLR) (AA 25-234) (Fc Tag)
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- Target See all Prolactin Receptor (PRLR) Proteins
- Prolactin Receptor (PRLR)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 25-234
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Prolactin Receptor protein is labelled with Fc Tag.
- Sequence
- AA 25-234
- Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.0 kDa. The protein migrates as 64 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product PRLR Protein
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Prolactin Receptor (PRLR) (AA 25-234) protein (His tag)
PRLR Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Prolactin Receptor (PRLR) (AA 25-236) protein (His tag)PRLR Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Prolactin Receptor (PRLR) (AA 20-229) protein (His tag)PRLR Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Prolactin Receptor (PRLR) (AA 25-235) protein (Fc Tag)PRLR Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Prolactin Receptor (PRLR) (AA 25-234) (Active) protein (His tag)PRLR Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Prolactin Receptor (PRLR) protein (Fc Tag)PRLR Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Prolactin Receptor (PRLR) (AA 371-479) protein (GST tag)PRLR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Prolactin Receptor (PRLR) (AA 1-622) protein (GST tag)PRLR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Prolactin Receptor (PRLR) protein (His tag)PRLR Origin: Rat Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
Prolactin Receptor (PRLR) protein (His tag,Fc Tag)PRLR Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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- Target
- Prolactin Receptor (PRLR)
- Alternative Name
- Prolactin R (PRLR Products)
- Synonyms
- hPRLrI Protein, PRL-R Protein, prlr Protein, PRLRb Protein, PRLR Protein, tprlr Protein, DKFZp469D061 Protein, RATPRLR Protein, AI987712 Protein, Pr-1 Protein, Pr-3 Protein, Prlr-rs1 Protein, wu:fj65c07 Protein, prolactin receptor Protein, prolactin receptor L homeolog Protein, prolactin receptor S homeolog Protein, prolactin receptor a Protein, PRLR Protein, prlr.L Protein, prlr.S Protein, PR Protein, prlr Protein, Prlr Protein, prlra Protein
- Background
- As a transmembrane receptor, the prolactin receptor (PRL-R) interacts with prolactin. In addition, the PRL-R also binds and is activated by growth hormone (GH) and human placental lactogen (hPL). Preclinical investigations, epidemiological studies and analyses of tissue specimens from patients strongly support the contribution of prolactin receptor (PRLR) signaling to breast and prostate tumorigenesis and cancer progression. Moreover, The PRLR has been found to be essential for lobuloalveolar maturation of the mammary glands during pregnancy, as evidenced by the fact that PRLR knockout mice show severely impaired development of lobuloalveolar structures.
- Molecular Weight
- 51.0 kDa
- NCBI Accession
- NP_000940
- Pathways
- JAK-STAT Signaling, Response to Growth Hormone Stimulus
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