TFAM Protein (AA 43-246) (His tag)
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- Target See all TFAM Proteins
- TFAM (Transcription Factor A, Mitochondrial (TFAM))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 43-246
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TFAM protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- TFAM, 43-246aa, Human, His tag, E.coli
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product TFAM Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol
- Storage
- 4 °C
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- Target
- TFAM (Transcription Factor A, Mitochondrial (TFAM))
- Alternative Name
- TFAM (TFAM Products)
- Synonyms
- tcf6 Protein, mttf1 Protein, mttfa Protein, tcf6l1 Protein, tcf6l2 Protein, tcf6l3 Protein, mttfa-A Protein, xl-mtTFA Protein, MGC153358 Protein, zgc:153358 Protein, MTTF1 Protein, MTTFA Protein, TCF6 Protein, TCF6L1 Protein, TCF6L2 Protein, TCF6L3 Protein, AI661103 Protein, Hmgts Protein, mtTFA Protein, tsHMG Protein, Mttfa Protein, transcription factor A, mitochondrial Protein, transcription factor A, mitochondrial L homeolog Protein, TFAM Protein, tfam.L Protein, tfam Protein, Tfam Protein
- Background
- TFAM, also known as MtTF1 or mtTFA, is a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. TFAM is located primarily in the nuclei of elongated spermatids and may be involved in the regulation of gene expression of the haploid male genome. TFAM has been associated with mitochondrial disorder in humans characterized by ocular myopathy, exercise intolerance and muscle wasting. Recombinant human TFAM protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Transcription factor A, mitochondrial precursor, MtTF1, mtTFA, TCF6, TCF6L1, TCF6L2, TCF6L3. NCBI no.: NP_003192
- Molecular Weight
- 26.6 kDa (225aa), confirmed by MALDI-TOF
- Pathways
- Chromatin Binding
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