DHODH Protein (His tag)
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- Target See all DHODH Proteins
- DHODH (Dihydroorotate Dehydrogenase (DHODH))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DHODH protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by using conventional chromatography.
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product DHODH Protein
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- Comment
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Synonyms: Dihydroorotate dehydrogenase (quinone), mitochondrial, DHOdehase, POADS, URA1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1 M NaCl, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- DHODH (Dihydroorotate Dehydrogenase (DHODH))
- Alternative Name
- DHODH (DHODH Products)
- Synonyms
- DHOdehase Protein, POADS Protein, URA1 Protein, 2810417D19Rik Protein, AI834883 Protein, DDBDRAFT_0167009 Protein, DDBDRAFT_0185217 Protein, DDB_0167009 Protein, DDB_0185217 Protein, DHOD Protein, DHODase Protein, XFHB_12025 Protein, dhodh Protein, dihydroorotate dehydrogenase (quinone) Protein, dihydroorotate dehydrogenase Protein, dihydroorotate dehydrogenase (quinone) L homeolog Protein, DHODH Protein, Dhodh Protein, pyrD Protein, pyr4 Protein, Mrub_0263 Protein, Arnit_2124 Protein, Trad_2703 Protein, Ftrac_1484 Protein, Ndas_0799 Protein, Mesil_1876 Protein, Slip_0841 Protein, Spirs_1436 Protein, XFHB_RS12780 Protein, dhodh.L Protein
- Background
- DHODH, also known as dihydroorotate dehydrogenase (quinone), mitochondrial, belongs to the dihydroorotate dehydrogenase family. DHODH catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. Recombinant human DHODH protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
- Molecular Weight
- 42.3 kDa (390aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_001352
- Pathways
- Ribonucleoside Biosynthetic Process, Protein targeting to Nucleus
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