VAMP2 Protein (AA 1-94) (His tag)

Catalog No. ABIN7281224

Product Details

Target: VAMP2 (Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2))

Protein Type: Recombinant

Protein Characteristics: AA 1-94

Origin: Mouse

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This VAMP2 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMSATAA TVPPAAPAGE GGPPAPPPNL TSNRRLQQTQ AQVDEVVDIM RVNVDKVLER DQKLSELDDR ADALQAGASQ FETSAAKLKR KYWWKNLK

Purity: > 90 % by SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: : Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 1  mM EDTA, 0.1  mM PMSF, 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: VAMP2 (Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2))

Alternative Name: Vamp2 (VAMP2 Products)

Synonyms: zgc:73302 Protein, wu:fj61c06 Protein, VAMP2 Protein, vamp2-a Protein, xsybi Protein, Syb-2 Protein, Syb2 Protein, sybII Protein, RATVAMPB Protein, RATVAMPIR Protein, SYB Protein, SYB2 Protein, VAMP-2 Protein, syb2 Protein, vamp2 Protein, xsybii Protein, vesicle-associated membrane protein 2 Protein, vesicle associated membrane protein 2 Protein, vesicle associated membrane protein 2 S homeolog Protein, vesicle-associated membrane protein 2 (synaptobrevin 2) Protein, vesicle associated membrane protein 2 L homeolog Protein, vamp2 Protein, VAMP2 Protein, vamp2.S Protein, Vamp2 Protein, vamp2.L Protein

Background: Vamp2, also known as Vesicle-associated membrane protein 2, is involved in the targeting and/or fusion of transport vesicles to their target membrane. It modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Vamp2 proteins localized to the cytoplasmic surface of synaptic vesicle, consists of a proline-rich N-terminal region, a highly conserved hydrophilic domain, followed by a transmembrane anchor and a C-terminal. This proteins also known to mediate cAMP-stimulated exocytosis in nerve cells and in renal cells of the juxtaglomerular apparatus. Recombinant mouse Vamp2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography

Molecular Weight: 12.8 kDa (118aa) Confirmed by MALDI-TOF

NCBI Accession: NP_033523

UniProt: P63044

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport