NMNAT1 Protein (AA 1-285) (His tag)
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- Target See all NMNAT1 Proteins
- NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-285
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NMNAT1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMDSSKKT EVVLLACGSF NPITNMHLRL FELAKDYMHA TGKYSVIKGI ISPVGDAYKK KGLIPAHHRI IMAELATKNS HWVEVDTWES LQKEWVETVK VLRYHQEKLA TGSCSYPQSS PALEKPGRKR KWADQKQDSS PQKPQEPKPT GVPKVKLLCG ITNDISSTKI RRALRRGQSI RYLVPDLVQE YIEKHELYNT ESEGRNAGVT LAPLQRNAAE AKHNHSTL
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product NMNAT1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In Phosphate buffered saline ( pH 7.4) containing 20 % glycerol, 1 mM EDTA
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))
- Alternative Name
- Nmnat1 (NMNAT1 Products)
- Synonyms
- id:ibd5068 Protein, im:7144541 Protein, zgc:110243 Protein, LCA9 Protein, NMNAT Protein, PNAT1 Protein, 2610529L11Rik Protein, 5730441G13Rik Protein, D4Cole1e Protein, nmnat Protein, nicotinamide mononucleotide adenylyltransferase 1 Protein, nicotinamide nucleotide adenylyltransferase 1 Protein, CpipJ_CPIJ015320 Protein, PTRG_06486 Protein, nmnat1 Protein, NMNAT1 Protein, Nmnat1 Protein
- Background
- Nmnat1, also known as nicotinamide/nicotinic acid mononucleotide adenylyltransferase1, is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) of nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD. It is widely expressed with high levels in skeletal muscle, heart, liver and kidney. This protein appears to have the ability to protect against axonal degeneration following mechanical or toxic insults. Recombinant mouse Nmnat1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
- Molecular Weight
- 34.7 kDa (308aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_597679
- UniProt
- Q9EPA7
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