TNFSF15 Protein (AA 72-251) (His tag)
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- Target See all TNFSF15 Proteins
- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 72-251
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TNFSF15 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- TNFSF15, 72-251aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product TNFSF15 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay )
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 50% glycerol, 0.2M NaCl
- Storage
- 4 °C
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- Target
- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
- Alternative Name
- TNFSF15 (TNFSF15 Products)
- Synonyms
- TTPAL Protein, TL1 Protein, TL1A Protein, VEGI Protein, VEGI192A Protein, Tl1 Protein, Tl1a Protein, Vegi Protein, tumor necrosis factor superfamily member 15 Protein, TNF superfamily member 15 Protein, tumor necrosis factor (ligand) superfamily, member 15 Protein, TNFSF15 Protein, Tnfsf15 Protein
- Background
- Tumor necrosis factor ligand superfamily member 15, also known TNFSF15, belongs to the TNF superfamily. TNFSF15 is predominantly expressed in endothelial cells and its expression is inducible by TNFalpha and IL1alpha. TNFSF15 is an angiogenesis inhibitor of the TNF family and functions in part by directly inhibiting endothelial cell proliferation. TNFSF15 may act as an autocrine factor to induce apoptosis in endothelial cells via activation of multiple signaling pathways, including stress protein kinases and certain caspases. Recombinant human TNFSF15 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Tumor necrosis factor ligand superfamily member 15, TL1, TL1A, VEGI, VEGI192A. NCBI no.: NP_005109
- Molecular Weight
- 22.7 kDa (201aa) confirmed by MALDI-TOF
- Pathways
- Positive Regulation of Endopeptidase Activity, Autophagy
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