HTRA2 Protein (full length) (His tag)
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- Target See all HTRA2 Proteins
- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
- Protein Type
- Recombinant
- Protein Characteristics
- full length
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HTRA2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- HtrA2/Omi 134-458 Human, Recombinant, His- tagged, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product HTRA2 Protein
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HtrA Serine Peptidase 2 (HTRA2) (AA 134-458) protein (His tag)
HTRA2 Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS
HtrA Serine Peptidase 2 (HTRA2) (AA 133-358) protein (His tag)HTRA2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
HtrA Serine Peptidase 2 (HTRA2) (AA 359-458) protein (GST tag)HTRA2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
HtrA Serine Peptidase 2 (HTRA2) (AA 134-458) protein (rho-1D4 tag)Crystallography grade HTRA2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
HtrA Serine Peptidase 2 (HTRA2) (AA 134-458) protein (rho-1D4 tag)Crystallography grade HTRA2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH 8.0), 50 mM NaCl, 1 mM DTT, 20% Glycerol
- Storage
- 4 °C
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- Target
- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
- Alternative Name
- HtrA2/Omi 134-458 (HTRA2 Products)
- Synonyms
- CG8464 Protein, DmHtrA2 Protein, Dmel\\CG8464 Protein, HtrA2/Omi Protein, Omi Protein, dOmi Protein, domi Protein, htrA2 Protein, omi Protein, HTRA2 Protein, PRSS25 Protein, OMI Protein, PARK13 Protein, AI481710 Protein, Prss25 Protein, mnd2 Protein, HTRA2-related serine protease Protein, HtrA serine peptidase 2 Protein, HtrA2 Protein, HTRA2 Protein, htra2 Protein, Htra2 Protein
- Background
- HtrA2/Omi is a mammalian serine protease at high temperatures and has a chaperone activity at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Mature HtrA2 consists of a putative transmembrane domain, an inhibitor of apoptosis protein (IAP)-binding motif, a single C-terminal PDZ domain that mediates protein-protein interactions. Recently, HtrA2 has known to contribute both to caspase-dependent and caspase-independent cell death. Mature form of HtrA2/Omi(residues 134-458) was overexpressed in E.coli, and purified by conventional column chromatography techniques. Synonyms: HTRA2, OMI, PRSS25, HtrA2/Omi, EC 3.4.21.108, High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine proteinase OMI, Serine protease 25, Serine protease HTRA2, mitochondrial, High temperature requirement protein A2. NCBI no.: NP_037379
- Molecular Weight
- 36kDa (334aa), confirmed by MALDI-TOF.
- Pathways
- Positive Regulation of Endopeptidase Activity
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