SRGN Protein (AA 28-158) (His tag)
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- Target See all SRGN Proteins
- SRGN (serglycin (SRGN))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-158
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SRGN protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- SRGN, 28-158 aa , Human, His tag E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product SRGN Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.15M NaCl.
- Storage
- 4 °C
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- Target
- SRGN (serglycin (SRGN))
- Alternative Name
- SRGN (SRGN Products)
- Synonyms
- PPG Protein, PRG Protein, PRG1 Protein, Prg Protein, Prg1 Protein, Sgc Protein, Pgsg Protein, serglycin Protein, SRGN Protein, Srgn Protein
- Background
- SRGN is a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. Recombinant human SRGN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Serglycin precursor, FLJ12930, MGC9289, PPG, PRG, PRG1. NCBI no.: NP_002718
- Molecular Weight
- 17.4 kDa (156aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
- Pathways
- Maintenance of Protein Location
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