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CDKN2C Protein (AA 1-168) (His tag)

CDKN2C Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667655
  • Target See all CDKN2C Proteins
    CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-168
    Origin
    • 7
    • 1
    Human
    Source
    • 4
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CDKN2C protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    CDKN2C, 1-168aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product CDKN2C Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 200mM NaCl
    Storage
    4 °C
  • Target
    CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))
    Alternative Name
    CDKN2C (CDKN2C Products)
    Synonyms
    CDKN2C Protein, p18 Protein, ink4c Protein, p18-ink4c Protein, INK4C Protein, p18-INK4C Protein, C77269 Protein, INK4c Protein, INK4d Protein, p18INK4c Protein, cyclin dependent kinase inhibitor 2C Protein, cyclin-dependent kinase inhibitor 2C Protein, cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) Protein, CDKN2C Protein, cdkn2c Protein, Cdkn2c Protein
    Background
    CDKN2C (Cyclin-dependent kinase 4 inhibitor C ) belongs to the CDKN2 cyclin-dependent kinase inhibitor family. It has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. And this protein suppresses the cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Recombinant human CDKN2C protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Cyclin-dependent kinase 4 inhibitor C, INK4C, p18, p18-INK4C. NCBI no.: NP_001253
    Molecular Weight
    20.7kDa (192aa), confirmed by MALDI-TOF
    Pathways
    Cell Division Cycle, Mitotic G1-G1/S Phases
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