NFKBIB Protein (AA 1-356) (His tag)
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- Target See all NFKBIB Proteins
- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-356
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NFKBIB protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- NFKBIB, 1-356aa , Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product NFKBIB Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
- Storage
- 4 °C
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- Target
- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
- Alternative Name
- NFKBIB (NFKBIB Products)
- Synonyms
- NFKBIB Protein, IKB-beta Protein, IKappaBbeta Protein, IkB Protein, IkBb Protein, IKBB Protein, TRIP9 Protein, NFKB inhibitor beta Protein, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta Protein, NFKBIB Protein, Nfkbib Protein
- Background
- NFKBIB, also known as NF-kappa-B inhibitor beta, belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Recombinant human NFKBIB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: IKBB, TRIP9. NCBI no.: NP_002494
- Molecular Weight
- 40.3 kDa (380aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
- Pathways
- NF-kappaB Signaling, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
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