SPOP-B Protein (AA 1-374) (His tag)
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- Target See all SPOP-B Proteins
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-374
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SPOP-B protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- SPOP, 1-374aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product SPOP-B Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 50% glycerol, 0.2M NaCl, 2mM EDTA
- Storage
- 4 °C
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- Target
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
- Alternative Name
- SPOP (SPOP-B Products)
- Synonyms
- BTBD32 Protein, TEF2 Protein, AI315626 Protein, Pcif1 Protein, zgc:64140 Protein, spop Protein, tef2 Protein, speckle type BTB/POZ protein Protein, speckle-type POZ protein Protein, speckle type POZ protein S homeolog Protein, SPOP Protein, Spop Protein, spop Protein, spop.S Protein
- Background
- SPOP (speckle-type POZ protein), also known as TEF2, is a member of the Tdpoz family containing one N-terminal MATH (Meprin and TRAF homology) domain and one C-terminal BTB/POZ domain. This protein inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex. Through an interaction with CUL-3, SPOP is involved in ubiquitinylation and protein degradation. Recombinant human SPOP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Speckle-type POZ protein, TEF2. NCBI no.: NP_001007231
- Molecular Weight
- 44.3kDa (394aa), confirmed by MALDI-TOF
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