IGSF11 Protein (AA 23-241) (Fc Tag)
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- Target See all IGSF11 Proteins
- IGSF11 (Immunoglobulin Superfamily, Member 11 (IGSF11))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 23-241
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IGSF11 protein is labelled with Fc Tag.
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IGSF11 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Storage
- -20 °C
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- Target
- IGSF11 (Immunoglobulin Superfamily, Member 11 (IGSF11))
- Alternative Name
- VSIG3 (IGSF11 Products)
- Synonyms
- sc:d812 Protein, seurat Protein, BT-IgSF Protein, CT119 Protein, CXADRL1 Protein, Igsf13 Protein, VSIG3 Protein, 1700025L02Rik Protein, immunoglobulin superfamily member 11 Protein, immunoglobulin superfamily member 11 L homeolog Protein, immunoglobulin superfamily, member 11 Protein, IGSF11 Protein, igsf11 Protein, igsf11.L Protein, Igsf11 Protein
- Background
- VSIG3, also known as IGSF11, BT-IgSF, and CLMP, is a homophilic adhesion molecule that preferentially expressed in the brain. The function of VSIG3 is to stimulate cell growth through homophilic interactions. In clinical, the VSIG3 has been reported to as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas. In addition, VSIG-3 is also a ligand of B7 family member VISTA/PD-1H and inhibits human T-cell functions through a novel VSIG-3/VISTA pathway. VSIG-3/VISTA co-inhibitory pathway may provide new strategies for the treatment of human cancers and autoimmune disorders.
- Molecular Weight
- 49.7 kDa
- NCBI Accession
- NP_001015887
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