Thymic Stromal Lymphopoietin Protein (TSLP) (AA 29-159) (Fc Tag)
Quick Overview for Thymic Stromal Lymphopoietin Protein (TSLP) (AA 29-159) (Fc Tag) (ABIN6950978)
Target
See all Thymic Stromal Lymphopoietin (TSLP) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 29-159
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Purification tag / Conjugate
- This Thymic Stromal Lymphopoietin protein is labelled with Fc Tag.
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Endotoxin Level
- Less than 0.1 EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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- Thymic Stromal Lymphopoietin (TSLP)
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Alternative Name
- TSLP
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Background
- Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases, and is widely expressed by epithelial cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence (4, 5). Human TSLP has been shown to developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic diseases and maintaining intestinal noninflammatory environment. Among diverse cells responding to Human TSLP, CD11c+ dendritic cells are the most obviously characterized target cells.
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Molecular Weight
- 41.6 kDa
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NCBI Accession
- NP_149024
Target
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