PD-1 Protein (AA 25-167) (Fc-His Tag)
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- Target See all PD-1 (PDCD1) Proteins
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-167
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PD-1 protein is labelled with Fc-His Tag.
- Application
- ELISA
- Purpose
- Recombinant human PD-1 protein with C-terminal human Fc and 6xHis tag
- Specificity
- PD-1 (Leu25-Gln167) hFc (Glu99-Ala330) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product PDCD1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- Alternative Name
- PD-1 (PDCD1 Products)
- Synonyms
- CD279 Protein, PD-1 Protein, PD1 Protein, SLEB2 Protein, hPD-1 Protein, hPD-l Protein, Ly101 Protein, Pdc1 Protein, programmed cell death 1 Protein, PDCD1 Protein, Pdcd1 Protein
- Background
- This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
- Molecular Weight
- predicted molecular mass of 42.9 kDa after removal of the signal peptide.
- Gene ID
- 5133
- UniProt
- Q15116
- Pathways
- Cancer Immune Checkpoints
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