2B4 Protein (Fc Tag)

Catalog No. ABIN6961162

Product Details

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This 2B4 protein is labelled with Fc Tag.

Application: ELISA

Purpose: Recombinant human 2B4 protein with C-terminal human Fc tag

Specificity: 2B4 (Cys22-Ala221) hFc (Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purification: affinity purification

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Preservative: Without preservative

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Alternative Name: 2B4 (CD244 Products)

Synonyms: CD244 Protein, 2B4 Protein, NAIL Protein, NKR2B4 Protein, Nmrk Protein, SLAMF4 Protein, C9.1 Protein, F730046O15Rik Protein, Ly90 Protein, CD244 molecule Protein, CD244 natural killer cell receptor 2B4 Protein, CD244 Protein, Cd244 Protein

Background: Synonymes: CD244, 2B4, SLAMF4, NKR2B4, NAIL, h2B4
Description: This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: predicted molecular mass of 47.7 kDa after removal of the signal peptide.

Gene ID: 51744

UniProt: Q9BZW8