ICOS Protein (Fc Tag)
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- Target See all ICOS Proteins
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ICOS protein is labelled with Fc Tag.
- Purpose
- Recombinant human ICOS protein with C-terminal human Fc tag
- Specificity
- ICOS (Glu21-Lys140) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- affinity purification
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product ICOS Protein
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Inducible T-Cell Co-Stimulator (ICOS) (AA 21-144) protein (Fc Tag)
ICOS Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (AA 21-141) protein (Fc Tag)ICOS Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (AA 21-134) protein (His tag)ICOS Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (Cys136Ser-Mutant), (Cys137Ser-Mutant) protein (His tag)ICOS Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (Cys137Ser-Mutant), (Cys138Ser-Mutant) protein (His tag)ICOS Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) protein (Fc Tag)ICOS Origin: Rhesus Monkey Host: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Inducible T-Cell Co-Stimulator (ICOS) (AA 1-168) protein (GST tag)ICOS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Inducible T-Cell Co-Stimulator (ICOS) (AA 21-140) protein (GST tag)ICOS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Inducible T-Cell Co-Stimulator (ICOS) protein (mFc-His Tag)ICOS Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Inducible T-Cell Co-Stimulator (ICOS) protein (Fc Tag)ICOS Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- Alternative Name
- ICOS (ICOS Products)
- Synonyms
- ICOS Protein, AILIM Protein, CCLP Protein, CRP-1 Protein, H4 Protein, Ly115 Protein, CD278 Protein, CVID1 Protein, Ailim Protein, inducible T-cell costimulator Protein, inducible T cell co-stimulator Protein, inducible T-cell co-stimulator Protein, ICOS Protein, LOC100232284 Protein, Icos Protein
- Background
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Synonymes: ICOS, CD278, AILIM, Inducible T-cell costimulator
Description: The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. - Molecular Weight
- predicted molecular mass of 39.7 kDa after removal of the signal peptide. The apparent molecular mass of ICOS-hFc is 55 kDa due to glycosylation.
- Gene ID
- 29851
- UniProt
- Q9Y6W8
- Pathways
- Cancer Immune Checkpoints
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