CLEC12A Protein (His tag)

Catalog No. ABIN6964075

Product Details

Target: CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CLEC12A protein is labelled with His tag.

Purpose: Recombinant human CLEC12A Protein with C-terminal 6xHis tag

Specificity: CLEC12A (His65-Ala265) 6xHis tag

Characteristics: Extracellular Domain Protein

Purification: affinity purification

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Preservative: Without preservative

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))

Alternative Name: CLEC12A (CLEC12A Products)

Synonyms: MGC179455 Protein, CLL-1 Protein, CLL1 Protein, DCAL-2 Protein, MICL Protein, D230024O04 Protein, KLRL1 Protein, Micl Protein, C-type lectin domain family 12 member A Protein, C-type lectin domain family 12, member a Protein, C-type lectin domain family 12, member A Protein, CLEC12A Protein, Clec12a Protein

Background: Synonymes: CLEC12A,MICL,CLL-1,CLL1,DCAL2,DCAL-2,CD371
Description: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13.

Molecular Weight: predicted molecular mass of 24.6 kDa after removal of the signal peptide.The apparent molecular mass of CLEC12A-His is 35-55 kDa due to glycosylation.

Gene ID: 160364

UniProt: Q5QGZ9