ITGB1 Protein (Fc Tag)

Catalog No. ABIN6964137

Product Details

Target: ITGB1 (Integrin beta 1 (ITGB1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ITGB1 protein is labelled with Fc Tag.

Purpose: Recombinant human ITGB1 protein with C-terminal human Fc tag

Specificity: ITGB1 (Gln21-Asp728) hFc (Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purification: affinity purification

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

The protein has a predicted molecular mass of 104.5 kDa after removal of the signal peptide.The apparent molecular mass of ITGB1-hFc is approximately 130-250 kDa due to glycosylation.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Preservative: Without preservative

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: ITGB1 (Integrin beta 1 (ITGB1))

Alternative Name: ITGB1 (ITGB1 Products)

Synonyms: CD29 Protein, FNRB Protein, GPIIA Protein, MDF2 Protein, MSK12 Protein, VLA-BETA Protein, VLAB Protein, 4633401G24Rik Protein, AA409975 Protein, AA960159 Protein, ENSMUSG00000051907 Protein, Fnrb Protein, Gm9863 Protein, gpIIa Protein, cd29 Protein, fnrb Protein, gpiia Protein, itgb1 Protein, mdf2 Protein, msk12 Protein, vla-beta Protein, vlab Protein, itgb1-a Protein, itgb1-b Protein, integrin subunit beta 1 Protein, integrin beta 1 (fibronectin receptor beta) Protein, integrin subunit beta 1 S homeolog Protein, integrin beta 1 Protein, integrin subunit beta 1 L homeolog Protein, ITGB1 Protein, Itgb1 Protein, itgb1.S Protein, LOC100009173 Protein, itgb1.L Protein

Background: Synonymes: CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB
Description: Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

Molecular Weight: predicted molecular mass of 104.5 kDa after removal of the signal peptide. The apparent molecular mass of ITGB1-hFc is 130-250 kDa due to glycosylation.

UniProt: P05556

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome