CRLF2 Protein (Fc Tag)
-
- Target See all CRLF2 Proteins
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CRLF2 protein is labelled with Fc Tag.
- Sequence
- CRLF2(Gln23-Lys231)+hFc(Glu99-Ala330)
- Characteristics
- Tagged Protein: C-Human Fc tag
- Purification
- affinity purification
- Top Product
- Discover our top product CRLF2 Protein
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -80 °C
- Storage Comment
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
- Expiry Date
- 12 months
-
- Target
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- Alternative Name
- CRLF2 (CRLF2 Products)
- Synonyms
- CRLF2 Protein, CRL2 Protein, CRLF2Y Protein, TSLPR Protein, CRLM2 Protein, Ly114 Protein, Tpte2 Protein, Tslpr Protein, Crl2 Protein, cytokine receptor like factor 2 Protein, cytokine receptor-like factor 2 Protein, CRLF2 Protein, Crlf2 Protein
- Background
-
Synonymes: CRL2, CRLF2Y, TSLPR
Description: This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene. - Molecular Weight
- 48.51 kDa
- UniProt
- Q9HC73
-