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CRLF2 Protein (Fc Tag)

CRLF2 Origin: Human Host: HEK-293 Cells Recombinant
Catalog No. ABIN6964184
  • Target See all CRLF2 Proteins
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    Protein Type
    Recombinant
    Origin
    • 12
    • 8
    • 1
    • 1
    Human
    Source
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CRLF2 protein is labelled with Fc Tag.
    Sequence
    CRLF2(Gln23-Lys231)+hFc(Glu99-Ala330)
    Characteristics
    Tagged Protein: C-Human Fc tag
    Purification
    affinity purification
    Top Product
    Discover our top product CRLF2 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Preservative
    Without preservative
    Storage
    -80 °C
    Storage Comment
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    Expiry Date
    12 months
  • Target
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    Alternative Name
    CRLF2 (CRLF2 Products)
    Synonyms
    CRLF2 Protein, CRL2 Protein, CRLF2Y Protein, TSLPR Protein, CRLM2 Protein, Ly114 Protein, Tpte2 Protein, Tslpr Protein, Crl2 Protein, cytokine receptor like factor 2 Protein, cytokine receptor-like factor 2 Protein, CRLF2 Protein, Crlf2 Protein
    Background
    Synonymes: CRL2, CRLF2Y, TSLPR
    Description: This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.
    Molecular Weight
    48.51 kDa
    UniProt
    Q9HC73
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