PRAME Protein (Fc Tag)
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- Target See all PRAME Proteins
- PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PRAME protein is labelled with Fc Tag.
- Sequence
- PRAME (Met1-Asn509)+hFc (Glu99-Ala330)
- Characteristics
- Tagged Protein: C-Human Fc tag
- Purification
- affinity purification
- Top Product
- Discover our top product PRAME Protein
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Preferentially Expressed Antigen in Melanoma (PRAME) (AA 1-509) protein (GST tag)
PRAME Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Preferentially Expressed Antigen in Melanoma (PRAME) (AA 321-420) protein (His-IF2DI Tag)PRAME Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Preferentially Expressed Antigen in Melanoma (PRAME) (AA 1-509) protein (Strep Tag)Crystallography grade PRAME Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Preferentially Expressed Antigen in Melanoma (PRAME) (AA 1-509), (full length) protein (His tag)PRAME Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Preferentially Expressed Antigen in Melanoma (PRAME) (AA 1-509), (full length) protein (His tag)PRAME Origin: Human Host: Yeast Recombinant > 90 % SDS
Preferentially Expressed Antigen in Melanoma (PRAME) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)PRAME Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -80 °C
- Storage Comment
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
- Expiry Date
- 12 months
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- Target
- PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
- Alternative Name
- PRAME (PRAME Products)
- Synonyms
- PRAME Protein, CT130 Protein, MAPE Protein, OIP-4 Protein, OIP4 Protein, 4930534P07Rik Protein, preferentially expressed antigen in melanoma Protein, PRAME Protein, Prame Protein
- Background
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Synonymes: CT130, MAPE, OIP-4, OIP4
Description: This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] - Molecular Weight
- 81.51 kDa
- UniProt
- P78395
- Pathways
- Retinoic Acid Receptor Signaling Pathway, Nuclear Hormone Receptor Binding
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