ROBO1 Protein (AA 26-897) (Fc Tag)
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- Target See all ROBO1 Proteins
- ROBO1 (Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-897
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ROBO1 protein is labelled with Fc Tag.
- Purpose
- Recombinant human ROBO1 protein with C-terminal human Fc tag
- Specificity
- ROBO1 (Gln26-Pro897) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product ROBO1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- ROBO1 (Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))
- Alternative Name
- ROBO1 (ROBO1 Products)
- Synonyms
- DUTT1 Protein, SAX3 Protein, AW494633 Protein, AW742721 Protein, Gm310 Protein, ROBO1 Protein, dutt1 Protein, roundabout Protein, sax3 Protein, MGC122264 Protein, roundabout-1 Protein, roundabout guidance receptor 1 Protein, roundabout, axon guidance receptor, homolog 1 (Drosophila) Protein, roundabout guidance receptor 1 L homeolog Protein, ROBO1 Protein, Robo1 Protein, robo1 Protein, robo1.L Protein
- Background
- Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
- Molecular Weight
- predicted molecular mass of 121.8 kDa after removal of the signal peptide. The apparent molecular mass of ROBO1-hFc is 100-130 kDa due to glycosylation.
- UniProt
- Q9Y6N7
- Pathways
- Positive Regulation of Endopeptidase Activity
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