ROBO1 Protein (FITC,His tag)
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- Target See all ROBO1 Proteins
- ROBO1 (Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ROBO1 protein is labelled with FITC,His tag.
- Purpose
- FITC-Labeled Human ROBO1 Protein, His Tag
- Sequence
- GIn 26 - Pro 897
- Characteristics
- FITC-Labeled Human ROBO1, His Tag is expressed from human 293 cells (HEK293). It contains AA GIn 26 - Pro 897 (Accession # Q9Y6N7-1).
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product ROBO1 Protein
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- Application Notes
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 97.5 kDa. The protein migrates as kDa under reducing (R) condition due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C, aviod light
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- Target
- ROBO1 (Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))
- Alternative Name
- ROBO1 (ROBO1 Products)
- Synonyms
- DUTT1 Protein, SAX3 Protein, AW494633 Protein, AW742721 Protein, Gm310 Protein, ROBO1 Protein, dutt1 Protein, roundabout Protein, sax3 Protein, MGC122264 Protein, roundabout-1 Protein, roundabout guidance receptor 1 Protein, roundabout, axon guidance receptor, homolog 1 (Drosophila) Protein, roundabout guidance receptor 1 L homeolog Protein, ROBO1 Protein, Robo1 Protein, robo1 Protein, robo1.L Protein
- Background
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Synonyms: ROBO1/DUTT1,
ROBO1 is a member of the ROBO immunoglobulin superfamily of proteins, and it plays a crucial role in cell motility and migration during embryogenesis and organogenesis. In addition, evidence showed that ROBO1 might drive migration and invasion in malignant cells, such as glioma and breast cancer, which might play a role in cancer aggressiveness. In contrast, some studies suggested that ROBO1 pathways play a key role in tumors by acting as a tumor suppressor, especially in cell invasion. - Molecular Weight
- 97.5 kDa
- Pathways
- Positive Regulation of Endopeptidase Activity
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