FASL Protein (Fc Tag)
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- Target See all FASL Proteins
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FASL protein is labelled with Fc Tag.
- Purpose
- Recombinant human FASLG with N-terminal human Fc tag
- Specificity
- HFc (Glu99-Ala330) FASLG (Pro134-Leu281)
- Characteristics
- Extracellular Domain Protein
- Purification
- affinity purification
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product FASL Protein
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Fas Ligand (TNF Superfamily, Member 6) (FASL) protein (His tag)
FASL Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 134-281) (Active) protein (His tag)FASL Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 1-281) protein (GST tag)FASL Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 172-281) protein (GST tag)FASL Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
- Alternative Name
- FASLG (FASL Products)
- Synonyms
- ALPS1B Protein, APT1LG1 Protein, APTL Protein, CD178 Protein, CD95-L Protein, CD95L Protein, FASL Protein, TNFSF6 Protein, fasl Protein, Fas-L Protein, Faslg Protein, Tnfsf6 Protein, gld Protein, Apt1Lg1 Protein, Fasl Protein, FASLG Protein, zgc:162027 Protein, Fas ligand Protein, Fas ligand L homeolog Protein, Fas ligand (TNF superfamily, member 6) Protein, FASLG Protein, faslg.L Protein, Fasl Protein, Faslg Protein, faslg Protein
- Background
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Synonymes: ALPS1B, APT1LG1, APTL, CD95-L, CD95L, CD178, FASL, TNFSF6, TNLG1A
Description: This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014] - Molecular Weight
- predicted molecular mass of 43.0 kDa after removal of the signal peptide. The apparent molecular mass of hFc-FASLG is 35-55kDa due to glycosylation.
- UniProt
- P48023
- Pathways
- Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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