IL18R1 Protein (Fc Tag)

Catalog No. ABIN6964389

Product Details

Target: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This IL18R1 protein is labelled with Fc Tag.

Purpose: Recombinant Human IL18RA Protein with C-terminal human Fc tag

Specificity: IL18RA (Ala19-Arg329) hFc (Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purification: affinity purification

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Preservative: Without preservative

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Alternative Name: IL18RA (IL18R1 Products)

Synonyms: CD218a Protein, CDw218a Protein, IL-1Rrp Protein, IL18RA Protein, IL1RRP Protein, IL-1R9 Protein, IL1R9 Protein, IL1RAPL-2 Protein, TIGIRR-1 Protein, Il18ralpha Protein, Il1rrp Protein, IL-18Ra Protein, IL18R1 Protein, interleukin 18 receptor 1 Protein, interleukin 1 receptor accessory protein like 2 Protein, IL18R1 Protein, IL1RAPL2 Protein, Il18r1 Protein

Background: Synonymes: CD218a, CDw218a, IL-1Rrp, IL-18R-alpha, IL-18Ralpha, IL1RRP, IL18RA, IL18Ralpha2
Description: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Molecular Weight: predicted molecular mass of 61.9 kDa after removal of the signal peptide.The apparent molecular mass of IL18RA-hFc is 55-70 kDa due to glycosylation.

UniProt: Q13478