Nucleoprotein (AA 1-448) protein (His tag)
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- Target
- Nucleoprotein
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-448
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Origin
- Human Coronavirus OC43 (HCoV-OC43)
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- His tag
- Purpose
- HCoV-OC43 Nucleocapsid protein, His Tag
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 40 mM PB, 500 mM NaCl, pH 7.4
- Storage
- -20 °C
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- Target
- Nucleoprotein
- Alternative Name
- Nucleocapsid protein
- Synonyms
- NP Protein, Protein N Protein, nucleocapsid protein Protein, N Protein
- Target Type
- Influenza Protein
- Background
- Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology, 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
- Molecular Weight
- 50.3 kDa
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