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Nucleoprotein (AA 1-377) protein (His tag)

Origin: Human Coronavirus NL63 (HCoV-NL63) Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN6992327
  • Target
    Nucleoprotein
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-377
    Origin
    • 1
    • 1
    Human Coronavirus NL63 (HCoV-NL63)
    Source
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    His tag
    Purpose
    HCoV-NL63 Nucleocapsid protein, His Tag
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    40 mM PB, 500 mM NaCl, pH 7.4
    Storage
    -20 °C
  • Target
    Nucleoprotein
    Alternative Name
    Nucleocapsid protein
    Synonyms
    NP Protein, Protein N Protein, nucleocapsid protein Protein, N Protein
    Target Type
    Influenza Protein
    Background
    Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology, 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
    Molecular Weight
    43.2 kDa
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