MADCAM1 Protein (AA 19-333) (Fc Tag)
-
- Target See all MADCAM1 Proteins
- MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 19-333
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MADCAM1 protein is labelled with Fc Tag.
- Purpose
- Human MAdCAM-1 Protein, Fc Tag (MALS verified)
- Purity
- >95 % as determined by reduced SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product MADCAM1 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
-
- Target
- MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
- Alternative Name
- MAdCAM-1 (MADCAM1 Products)
- Synonyms
- MACAM1 Protein, AV211525 Protein, mucosal vascular addressin cell adhesion molecule 1 Protein, MADCAM1 Protein, Madcam1 Protein
- Background
- The mucosal addressin cell adhesion molecule-1 (MAdCAM-1) takes a key role in the endothelial adhesion and migration of lymphocytes to sites of inflammation in inflammatory disease. In vitro and in vivo data indicate that blockade of the adhesion molecule mucosal address in cell adhesion molecule (MAdCAM) pathway decreases leukocyte homing to the gut by inhibiting the interaction between MAdCAM and its ligand the α4β7 integrin expressed on lymphocytes.
- Molecular Weight
- 59.6 kDa
-