IL-2 R beta & IL-2 R alpha & IL-2 R gamma (AA 27-239) (Active) protein (His tag,Twin-Strep tag)
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- Target
- IL-2 R beta & IL-2 R alpha & IL-2 R gamma
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 27-239
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Origin
- Rat
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- His tag,Twin-Strep tag
- Purpose
- Rat IL-2 R beta&IL-2 R alpha&IL-2 R gamma Protein, His Tag&Twin-Strep Tag (MALS verified)
- Purity
- >95 % as determined by reduced SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- IL-2 R beta & IL-2 R alpha & IL-2 R gamma
- Background
- Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
- Molecular Weight
- 30.2 kDa & 59.3 kDa
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