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GFRAL Protein (His tag)

GFRAL Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7092777
  • Target See all GFRAL Proteins
    GFRAL (GDNF Family Receptor alpha Like (GFRAL))
    Protein Type
    Recombinant
    Origin
    • 5
    • 4
    • 2
    Human
    Source
    • 7
    • 4
    HEK-293 Cells
    Purification tag / Conjugate
    This GFRAL protein is labelled with His tag.
    Purpose
    Recombinant human GFRAL protein with C-terminal 6xHis tag
    Specificity
    GFRAL (Ser19-Glu351) 6xHis tag
    Characteristics
    Extracellular Domain Protein
    Purification
    affinity purification
    Purity
    The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product GFRAL Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    GFRAL (GDNF Family Receptor alpha Like (GFRAL))
    Alternative Name
    GFRAL (GFRAL Products)
    Synonyms
    RGD1565220 Protein, C6orf144 Protein, GRAL Protein, UNQ9356 Protein, bA360D14.1 Protein, AY457637 Protein, Gral Protein, GDNF family receptor alpha like Protein, Gfral Protein, GFRAL Protein
    Background
    Synonymes: bA360D14.1
    Description: Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.[UniProtKB/Swiss-Prot Function]
    Molecular Weight
    predicted molecular mass of 38.6 kDa after removal of the signal peptide. The apparent molecular mass of GFRAL-His is 35-55 kDa due to glycosylation.
    UniProt
    Q6UXV0
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